Activity 1: Genome Tools – Annotation and functional analysis for genes and complex
WP 1.1 Transcriptome of full length cDNAs
WP 1.2 SNPs and haplotypes for assisting complex trait analysis
WP 1.2 SNPs and haplotypes for assisting complex trait analysis
Activity 2: Nuclear transfer in the rat
WP 2.1 Characterisation of early rat embryos
WP 2.2 Preparation/optimisation of nuclear donor cells
WP 2.3 Screening potential nucleus donor cells
WP 2.2 Preparation/optimisation of nuclear donor cells
WP 2.3 Screening potential nucleus donor cells
Activity 3: Rat biological resources and toxicogenetics
WP 3.1 Provision of a repository of live and frozen rat strains
WP 3.2 Toxicogenetics and pharmacogenetics
WP 3.3 Rat heterogeneous stock (HS)
WP 3.2 Toxicogenetics and pharmacogenetics
WP 3.3 Rat heterogeneous stock (HS)
Activity 4: Rat genome informatics
WP 4.1 Development of data mining resources
WP 4.2 User survey, training and use-case development
WP 4.2 User survey, training and use-case development
Activity 5: Gene expression analysis as tool for gene identification
WP 5.1 Gene expression in congenic strains
WP 5.2 Gene expression in recombinant inbred strains
WP 5.3 Microarray data management
WP 5.4 Proteomics
WP 5.2 Gene expression in recombinant inbred strains
WP 5.3 Microarray data management
WP 5.4 Proteomics
Activity 6: Rat gene discovery and applications of the rat model to human disease
WP 6.1 Cardiovascular diseases
WP 6.2 Inflammatory diseases
WP 6.2 Inflammatory diseases