Publications
- Aitman T, Critser JK, Dominiczak A, Cuppen E, Fernandez XM, Geurts AM, Gould M, Harris PC, Holmdahl R, Hübner N, Izsvak Z, Jacob H, E. Kwitek AE, Marrone A, Mashimo T, Moreno C, Mullins J, Mullins L, Olsson T, Riley L, Saar K, Serikawa T, Shull JD, Szpirer C, Voigt B, Worley K (2008): Progress and prospects in rat genetics: a community view.Nat Genet, 40(5), 516-522.

- Aitman TJ, Petretto E, Behmoaras J (2010): Genetic mapping and positional cloning.Methods Mol Biol. 2010;597:13-32.

- Atanur S, Birol, I, Guryev V, Hirst M, Hummel O, Morrissey C, Behmoaras J, Fernandez X, Johnson MD, McLaren W, Patone G, Petretto E, Plessy C, Rockland KS, Rockland C, Saar K, Zhao Y, Carnici P, Flicek P, Kurtz T, Cuppen E, Pravenec M, Hubner N, Jones SJM, Birney E, Aitman TJ (2010). The genome sequence of the spontaneously hypertensive rat: analysis and functional significance. Genome Research, 20(6): 791-803.

- Bader M (2010): Rat models of cardiovascular diseases.Methods Mol Biol. 597:403-14.

- Behmoaras J, Bhangal G, Smith J, McDonald K, Mutch B, Chin Lai P, Domin J, Game L, Salama A, Foxwell BM, Pusey CD, Cook HT, Aitman TJ (2008): JunD is a determinant of macrophage activation and glomerulonephritis susceptibility.Nat Genet, 40(5), 553-559.

- Behmoaras J, Smith J, D’Souza Z, Bhangal G, Chawanasuntorapoj R, Tam F, Pusey C, Aitman TJ, Cook HT (2010): Genetic loci modulate macrophage activity and glomerular damage in experimental glomerulonephritis.J Am Soc Nephrol. 21(7):1136-44.

- Bereczky Veress B, Lidman O, Sabri F, Bergström T, Spenger C, Olsson T, Piehl F, Diez M, Sköldenberg B (2008): Genetic background influences susceptibility to Herpes simplex virus type 1 encephalitis at the level of uptake/transport in a novel rat model.J Neurovir, 14(2):102-18.

- Bereczky-Veress B, Abdelmagid N, Piehl F, Bergström T, Olsson T, Sköldenberg B, Diez M (2010): Importance of Perineurial Cells and Toll-Like Receptors 2 and 9 in Herpes simplex Type 1 Encephalitis. Plos One, 27;5(8):e12350.

- Beyeen AD, Gillett A, Thessen Hedreul M, Olsson T and Jagodic M (2010): Epistatic Interaction between Genetic Variants in Raet1l and Klrk1 Determines NK cell Regulation of Neuroinflammation. submitted
- Beyeen AD, Zeitelhofer-Adzemovic M, Öckinger J, Stridh P, Becanovic K, Lassmann H, Harris R, Hillert J, Alfredsson L, Kockum I, Jagodic M, Olsson T (2010). IL22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.J. Immunol., Epub ahead of print.

- Brittain JF, McCabe C, Bridges LR, Holmes WM, Graham D, Khatun H, Szewczyk KA, Dominiczak AF, Macrae IM, Hainsworth AH (2010): A neuroradiological and neuropathological study of aged stroke-prone spontaneously hypertensive rats (SHRSP).submitted
- Buresova M, Zidek V, Musilova A, Simakova M, Fucikova A, Bila V, Kren V, Kazdova L, Di Nicolantonio R, Pravenec M (2006): Genetic relationship between placental and fetal weights and markers of the metabolic syndrome in reat recombinant inbred strains.Physiol Genomics, 26, 226-32.

- Calcios C, Casemayou A, Dejean AS, Gaits Iacovuni F,Pedros C, Bernard I, Lagrange D, Deckert M, Lamourox L, Jagodic M, Olsson T, Liblau RS Fournie G, Saoudi A (2010). The p.Arg63TRP polymorphism controls Vav1 functions and Foxp# regulatory T cell development.submitted.
- Campbell DJ, Karam H, Ménard J, Bruneval P, Mullins JJ (2009): Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver.Hypertension. 54(6):1248-53.

- Carrasco J, Marquez C, Nadal R, Tobeña A, Fernandez-Teruel A, Armario A (2008): Characterization of central and peripheral components of the hypothalamus-pituitary-adrenal axis in the inbred Roman rat strains.Psychoneuroendocrinology, 33(4):437-45.

- Chuykin I, Lapidus I, Popova E, Vilianovich L, Mosienko V, Alenina N, Binas B, Chai G, Bader M, Krivokharchenko A (2010): Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos. PLoS ONE, 5(3):e9794.

- Cozzi J, Wang E, Jacquet C, Fraichard A, Cherifi Y, Zhou Q (2010): Procedures for somatic cell nuclear transfer in the rat.Methods Mol Biol. 2010;597:137-50.

- Diez M, Abdelmagid N, Harnesk K, Ström M, Lidman O, Swanberg M, Lindblom R, Al-Nimer F, Jagodic M, Olsson T, Piehl F (2009): Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury.Journal of Neuroimmunology, 212(1-2):82-92.

- Dominguez C, Lidman O, Hao JX, Diez M, Tuncel J, Olsson T, Wiesenfeld- Hallin Z, Piehl F, Xu XJ (2008): Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia.Pain, 136(3):313-9.

- Dominguez CA, Li L, Lidman O, Olsson T, Wiesenfeld-Hallin Z, Piehl F, Xu XJ (2008): Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats.Neurosci Lett, 442(3):284-6.

- Dominguez CA, Lidman O, Olsson T, Wiesenfeld-Hallin Z, Piehl F, Xu XJ (2008) Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats.Neurosci Lett, 443(2):95-8.

- Drahota Z, Vrbacký M, Nůsková H, Kazdová L, Zídek V, Landa V, Pravenec M, Houstek J. (2010): Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain.Biochem Biophys Res Commun. 391(3):1348-51.

- Drahota Z, Vrbacký M, Nůsková H, Kazdová L, Zídek V, Landa V, Pravenec M, Houstek J. (2010): Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain.Biochem Biophys Res Commun, 391(3):1348-51

- Dunbar DR, Khaled H, Evans LC, Al-Dujaili EA, Mullins LJ, Mullins JJ, Kenyon CJ, Bailey MA (2010): Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney. Physiol Genomics. 4;40(3):158-66.

- Fanciulli M, Norsworthy P, Petretto E, Dong R, Harper L, Kamesh L, Heward J, Gough S, de Smith A, Blakemore A, Froguel P, Owen C, Pearce S, Teixeira L, Guillevin L, Cunninghame Graham D, Pusey C, Cook T, Vyse T, Aitman T (2007): FCGR3B copy number variation is associated with susceptibility to systemic but not organ-specific autoimmunity. Nat Genet, 39(6), 721-3.

- Gelderman KA, Hultqvist M, Olsson LM, Bauer K, Pizzolla A, Olofsson P, Holmdahl R (2007): Rheumatoid Arthritis: The Role of Reactive Oxygen Species in Disease Development and Therapeutic Strategies.Antioxid Redox Signal, 9(10):1541-67.

- Gillett A, Marta M, Jin Tao, Tuncel J, Leclerc P, Nohra R, Lange S, Holmdahl R, Olsson T, Harris RA, Jagodic M (2010): TNF production in macrophages is genetically determined and regulates inflammatory disease in rats. J Immunol. 185(1):442-50.

- Gillett A, Thessen Hedreul M, Khademi M, Espinosa A, Beyen AD, Jagodic M, Kockum I, Harris RA, Olsson T (2010): Interleukin 18 receptor 1 expression distinguishes patients with multiple sclerosis.Mult Scler. 16(9):1056-65.

- Gómez MA, de la Torre L, Callejas-Aguilera JE, Lerma-Cabrera JM, Rosas JM, Escarabajal MA, Agüero A, Tobeña A, Fernández-Teruel A, Torres C (2008): The partial reinforcement extinction effect (PREE) in female Roman high- (RHA-I) and low-avoidance (RLA-I) rats.Behav Brain Res. 194(2):187-92.

- Gómez MJ, de la Torre L, Callejas-Aguilera JE, Rosas JM, Escarabajala MD, Agüero A, Tobeña A, Fernández-Teruel A, Torres C (2009): Differences in Extinction of an Appetitive Instrumental Response in Female Inbred Roman High- (RHA-I) and Low- (RLA-I) Avoidance Rats.Psicológica 30:181-188.
- Gómez MJ, Escarabajal MD, de la Torre L, Tobeña A, Fernández-Teruel A, Torres C (2009): Consummatory successive negative and anticipatory contrast effects in inbred Roman rats.Physiol Behav. 97(3-4):374-80.

- Gómez MJ, Morón I, Torres C, Esteban FJ, de la Torre L, Cándido A, Maldonado A, Fernández-Teruel A, Tobeña A, Escarabajal MD (2009): One-way avoidance acquisition and cellular density in the basolateral amygdala: strain differences in Roman high- and low-avoidance rats.Neurosci Lett. 450(3):317-20.

- Graham D, Huynh NN, Hamilton CA, Beattie E, Smith RA, Cochemé HM, Murphy MP, Dominiczak AF (2009). Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy.Hypertension, 54(2):322-8.

- Graham D, McBride MW, Gaasenbeek M, Gilday K, Beattie E, Miller WH, McClure JD, Polke JM, Montezano A, Touyz RM, Dominiczak AF (2007): Candidate Genes That Determine Response to Salt in the Stroke-Prone Spontaneously Hypertensive Rat. Congenic Analysis.Hypertension, 50(6), 1134-41.

- Grieve IC, Dickens NJ, Pravenec M, Kren V, Hubner N, Cook SA, Aitman TJ, Petretto E, Mangion J (2008): Genome-wide co-expression analysis in multiple tissues.PLoS ONE, 3(12):e4033.

- Guryev V, Saar K, Adamovic T, Verheul M, van Heesch S, Cook S, Pravenec M, Aitman T, Jacob H, Shull JD, Hubner N, Cuppen E (2008): Selection Bias and Functional Impact of DNA Copy Number Variation in the Rat.Nat Genet, 40(5), 538-545.

- Harnesk K, Swanberg M, Öckinger J, Diez M, Lidman O, Lobell A, Wallström E, Olsson T, Piehl F (2008): Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis. J Immunol, 180(5), 3289-96.

- Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley SR, Bauerfeind A, Hummel O, Lee YA, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray EE, Cyster JG; Cardiogenics Consortium, Erdmann J, Hengstenberg C, Maouche S, Ouwehand WH, Rice CM, Samani NJ, Schunkert H, Goodall AH, Schulz H, Roider HG, Vingron M, Blankenberg S, Münzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth DJ, Pravenec M, Aitman TJ, Cambien F, Clayton D, Todd JA, Hubner N, Cook SA (2010): A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.Nature. 467(7314):460-4.

- Holmdahl R (2008): IL-21 and autoimmune disease - hypothesis and reality?Eur J Immunol. 38(7):1800-1802.

- Hopcroft LEM, McBride MW, Harris KJ, Sampson AK, McClure JD, Graham D, Young G, Holyoake TL, Girolami MA, Dominiczak AF. Predictive response-relevant clustering of expression data provides insights into disease processes.Nucleic Acids Res. Jun 22, 2010. [Epub ahead of print]

- Huberle A, Beyeen AD, Ockinger J, Ayturan M, Jagodic M, de Graaf KL, Fissolo N, Marta M, Olofsson P, Hultqvist M, Holmdahl R, Olsson T, Weissert R (2010): Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome.J Immunol. 182(7):4432-8.

- Jagodic M, Colacios C, Nohra R, Dejean AS, Beyeen AD, Khademi M, Casemayou A, Lamouroux L, Duthoit C, Sjoholm L, Bernard I, Lagrange D, Dahlman I, Lundmark F, Oturai AB, Soendergaard HB, Kempinen A, Saarela J, Ienari P, Harbo HF, Spurkland A, Ramagopalan S, Sadovnick DA, Ebers G, Seddighzadeh M, Klareskog L, Alfredsson L, Padyukov L, Hillert J, Clanet M, Edan G, Fontaine B, Fournie GJ, Saoudi A, Kockum I, Olsson T (2009): A role for Vav1 in experimental autoimmune encephaphalomuyelitis and Multiple Sclerosis.Science Translational Medicine, 1(10), 1-11

- Jagodic, M, Olsson T (2006): Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat. Genomics, 88(6), 737-44.

- Jirout ML, Friese RS, Mahapatra NR, Mahata M, Taupenot L, Mahata SK, Kren V, Zídek V, Fischer J, Maatz H, Ziegler MG, Pravenec M, Hubner N, Aitman TJ, Schork NJ, O'Connor DT (2010): Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat.Hum Mol Genet. 19(13):2567-80.

- Johannesson M, Lopez-Aumatell R, Stridh P, Diez M, Tuncel J, Blazquez G, Martinez E, Canete A, Vicens-Costa E, Graham D, Copley RP, Hernandez-Pliego P, Beyeen AD, Öckinger J, Fernandez C, Gulko PS, Brenner M, Tobeña A, Guitart-Masip M, Gimenez-Llort L, Dominiczak A, Holmdahl R, Gauguier D, Olsson T, Mott R, Valdar W, Redei E, Fernandez-Teruel A, Flint F (2009): A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.Genome Research, 19(1):150-8.

- Johnson MD, He L, Herman D, Wakimoto H, Wallace CA, Zidek V, Mlejnek P, Musilova A, Simakova M, Vorlicek J, Kren V, Viklicky O, Qi NR, Wang J, Seidman CE, Seidman J, Kurtz TW, Aitman TJ, Pravenec M (2009): Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat.Hypertension, 54(3):639-45

- Koh-Tan HH, Graham D, Hamilton CA, Nicoll G, Fields L, McBride MW, Young B, Dominiczak AF(2009): Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure.J Hypertens. 27(8):1575-84

- Krupková M, Sedová L, Liska F, Krenová D, Kren V, Seda O (2010): Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions.Lipids Health Dis. 9:38.

- Kurtz TW, Pravenec P (2008): Molecule specific effects of angiotensin II receptor blockers independent of the renin angiotensin system.Am J Hypertens, 21(8), 852-9.

- Landa V, Zídek V, Pravenec M (2010): Generation of rat "supersonic" congenic/conplastic strains using superovulation and embryo transfer.Methods Mol Biol. 2010;597:267-75.

- Lella V, Stieber D, Riviere M, Szpirer J, Szpirer C (2007): Mammary cancer resistance and precocious mammary differentiation in the WKY rat: identification of 2 quantitative trait loci.Int J Cancer, 121(8), 1738-42.

- Liska F, Snajdr P, Sedová L, Seda O, Chylíková B, Slámová P, Krejcí E, Sedmera D, Grim M, Krenová D, Kren V. (2009): Deletion of a conserved noncoding sequence in Plzf intron leads to Plzf down-regulation in limb bud and polydactyly in the rat.Dev Dyn. 238(3):673-84.

- Liu X, Bellamy CO, Bailey MA, Mullins LJ, Dunbar DR, Kenyon CJ, Brooker G, Kantachuvesiri S, Maratou K, Ashek A, Clark AF, Fleming S, Mullins JJ (2009): Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. J Biol Chem. 5;284(23):15564-72.

- Lopez-Aumatell R, Blazquez G, Gil L, Aguilar R, Gimenez-Llort L, Tobeña A, Fernandez-Teruel A (2009): The Roman rat strains differ in fear-potentiated startle and fear conditioning to cues and contexts.Psicothema, 21(1):27-32.

- Lopez-Aumatell R, Guitart-Masip M, Vicens-Costa E, Gimenez-Llort L, Valdar W, Johannesson M, Flint J, Tobeña A, Fernandez-Teruel A (2008): Fearfulness in a large N/Nih genetically heterogeneous rat stock: Differential profiles of timidity and defensive flight in males and females.Behav Brain Res, 188(1), 41-55.

- Lopez-Aumatell R, Guitart-Masip M, Vicens-Costa E, Gimenez-Llort L, Valdar W, Johannesson M, Flint J, Tobeña A, Fernandez-Teruel A (2007): Fearfulness in a large N/Nih genetically heterogeneous rat stock: Differential profiles of timidity and defensive flight in males and females.Behav Brain Res, epub 26.10.2007.

- López-Aumatell R, Vicens-Costa E, Guitart-Masip M, Martínez-Membrives E, Valdar W, Johannesson M, Cañete T, Blázquez G, Driscoll P, Flint J, Tobeña A, Fernández-Teruel A (2009): Unlearned anxiety predicts learned fear: a comparison among heterogeneous rats and the Roman rat strains. Behav Brain Res.;202(1):92-101.

- Malínská H, Oliyarnyk O, Hubová M, Zídek V, Landa V, Simáková M, Mlejnek P, Kazdová L, Kurtz TW, Pravenec M (2010): Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis.Mol Cell Biochem, 335(1-2):119-25.

- Manning JR, Hedley A, Mullins JJ, Dunbar DR (2009): Automated seeding of specialised wiki knowledgebases with BioKb. BMC Bioinformatics. 10:291.

- Marta M, Stridh P, Becanovic K, Jagodic M, Ockinger J, Sheng JR, Nohra R, Lorentzen JC, Olsson T (2010): Multiple loci comprising immune-related genes regulate experimental neurinflammation.Genes and Immunity, 11(1):21-36

- Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gösele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck W-H, Luft FC, Hubner N (2008): Soluble epoxide hydrolase (Ephx2) is a susceptibility gene for heart failure in a rat model of human disease,Nat Genet, 40(5), 529-537.

- Moreno M, Cardona D, Gómez MJ, Sánchez-Santed F, Tobeña A, Fernández-Teruel A, Campa L, Suñol C, Escarabajal MD, Torres C, Flores P (2010): Impulsivity characterization in the Roman high- and low-avoidance rat strains: behavioral and neurochemical differences.Neuropsychopharmacology. 35(5):1198-208.

- Morón I, Gómez MA, Escarabajal MA, de la Torre L, Cándido A, Maldonado A, Tobeña A, Fernández-Teruel A, Torres C (2010): One-way avoidance learning in female inbred Roman high- and low-avoidance rats: effects of bilateral electrolytic central amygdala lesions.Neurosci Lett. 474(1):32-6.

- Nohra R, Beyeen AD, Guo JP, Khademi M, Sundqvist E, Hedreul MT, Sellebjerg F, Smestad C, Oturai AB, Harbo HF, Wallström E, Hillert J, Alfredsson L, Kockum I, Jagodic M, Lorentzen J, Olsson T (2010): RGMA and IL21R show association with experimental inflammation and multiple sclerosis.Genes and Immunity,11(4):279-93.

- Olsson T, Jagodic M, Piehl F, Wallström E (2006): Genetics of autoimmune neuroinflammation. Curr Opin Immunol, 18(6), 643-9.

- Petretto E, Bottolo L, Langley S, Heinig M, McDermott-Roe C, Sarwar R, Pravenec M, Hubner N, Aitman TJ, Cook SA, Richardson S (2010). New insights into the genetic control of gene expression using a Bayesian multi-tissue approach.PLoS Computational Biology, 6(4):e1000737.

- Petretto E, Mangion J, Dickens N, Cook S, Mandek K, Lu H, Fischer J, Maatz H, Kren V, Pravenec M, Hubner N, Aitman T (2006): Heritability and Tissue-Specificity of Expression QTLs.PLoS Genetics, 2(10), 1625-33.

- Petretto E, Mangion J, Pravenec M, Hubner N, Aitman T (2006): Integrated gene expression profiling and linkage analysis in the rat.Mamm Genome, 17, 480-9.

- Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz TW, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA (2008): Integrated genomic approaches identify osteoglycin (Ogn) as a novel determinant of left ventricular mass.Nat Genet, 40(5), 546-552.

- Piehl F, Olsson T (2009) Inflammation and susceptibility to neurodegeneration: The use of unbiased genetics to decipher critical regulatory pathways.Neuroscience. 158(3):1143-50.

- Piessevaux G, Lella V, Rivière M, Stieber D, Szpirer J, Szpirer C (2009): Contrasting epistatic interactions between rat quantitative trait loci controlling mammary cancer development.Mamm Genome, 20(1):43-52.

- Popova E, Bader M, Krivokharchenko A (2006): Full-term development of rat after transfer of nuclei from two-cell stage embryos.Biol Reprod, 74(4), 524-30.

- Popova E, Bader M, Krivokharchenko A (2009): Efficient production of nuclear transferred rat embryos by modified methods of reconstruction.Mol Reprod Dev. 76, 208-216.

- Popova E, Rentzsch B, Bader M, Krivokharchenko A (2008): Generation and characterization of a GFP transgenic rat line for embryological research. Transgenic Res. 17, 955-963.

- Pravenec M (2010): Use of rat genomics for investigating the metabolic syndrome. Methods Mol Biol, 597:415-26.

- Pravenec M, Hyakukoku M, Houstek J, Zidek V, Landa V, Mlejnek P, Miksik I, Dudová-Mothejzikova K, Pecina P, Vrbacký M, Drahota Z, Vojtiskova A, Mracek T, Kazdova L, Oliyarnyk O, Wang J, Ho C, Qi N, Sugimoto K, Kurtz TW (2007): Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains.Genome Res, 17(9), 1319-26.

- Pravenec M, Kazdova L, Landa V, Zidek V, Mlejnek P, Simakova M, Jansa P, Forejt J, Kren V, Krenova D, Qi N, Wang J, Chan D, Aitman TJ, Kurtz TW (2008): Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat.Hypertension 51,148-153.

- Pravenec M, Kazdová L, Maxová M, Zídek V, Mlejnek P, Simáková M, Kurtz TW (2008): Long-term pioglitazone treatment enhances lipolysis in rat adipose tissue. Int J Obes, 32(12):1848-53.

- Pravenec M, Kurtz TW (2010): Recent advances in genetics of the spontaneously hypertensive rat.Curr Hypertens Rep, 12:5-9.

- Pravenec M, P.C.Churchill PC, M.C.Churchill MC, O.Viklicky O, L.Kazdova L, T.J.Aitman TA, E.Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, K.Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW (2008): Identification of renal /Cd36 /as a determinant of blood pressure and risk for hypertension. Nat Genet, 40(8):952-4.

- Pravenec M, Petretto E (2008): Insight into the genetics of hypertension, a core component of the metabolic syndrome.Curr Opin Clin Nutr Metab Care, 11(4):393-7.

- Rintisch C, Ameri J, Olofsson P, Luthman H, Holmdahl R. (2008): Positional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats.Proc Natl Acad Sci U S A. 105(37):14005-10.

- Rintisch C, Förster M, Holmdahl R (2009): Detection of arthritis-susceptibility loci, including Ncf1, and variable effects of the major histocompatibility complex region depending on genetic background in rats.Arthritis Rheum.60(2):419-27.

- Rintisch C, Holmdahl R (2008) DA rats from two colonies differ genetically and in their arthritis susceptibility.Mamm Genome. 19(6):420-428.

- Rintisch C, Kelkka T, Norin U, Lorentzen JC, Olofsson P, Holmdahl R (2010): Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus.Genes Immun. 11(3):239-45.

- STAR consortium, Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y, Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M, Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M, Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N. (2008): SNP and haplotype mapping for genetic analysis in the Rat. Nat Genet, 40(5), 560-566.

- Stridh P, Thessen Hedreul M, Beyeen AD, Adzemovic MZ, Laaksonen H, Gillett A, Ockinger J, Marta M, Lassmann H, Becanovic K, Jagodic M, Olsson T (2010). Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat.. Plos One, 15;5(9):e12716.

- Sugimoto K, Kazdová L, Qi NR, Hyakukoku M, Křen V, Simáková M, Zídek V, Kurtz TW, Pravenec M (2008): Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.J Hypertens 26(6), 1209-1215.

- Szpirer C (2010): Cancer research in rat models. Methods Mol Biol. 2010;597:445-58.

- Szpirer C and Levan G (2010): Rat genome mapping and genomics. In: "Genome Mapping and Genomics in Laboratory animals", P. Denny and C. Kole eds. Springer, in press
- Szpirer C, Lella V, Rivière M, De Mees C, Szpirer J (2010): Association of mammary cancer resistance with upregulation of DNA damage response genes. The Open Cancer J., in press
- Szpirer C, Szpirer J (2007): Mammary cancer susceptibility: human genes and rodent models.Mamm Genome, 18(12), 817-31.

- Tomlinson C, Thimma M, Alexandrakis S, Castillo T, Dennis JL, Brooks A, Bradley T, Turnbull C, Blaveri E, Barton G, Chiba N, Maratou K, Soutter P, Aitman TJ, Game L. (2008): MiMiR: an integrated platform for microarray data sharing, mining and analysis. BMC Bioinformatics18;9:379.

- Twigger SN, Pruitt KD, Fernandez-Suarez XM, Karolchik D, Worley K, Maglott D, Brown G, Weinstock G, Gibbs R, Kent J, Birney E, Jacob HJ (2008): What everybody should know about the Rat Genome and its online resources.Nat Genet, 40(5), 523-527.

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